Leptavoid H vaccine

Product Description

For the active immunisation of cattle from 1 month of age against Leptospira interrogans serovar Hardjo and Leptospira borgpetersenii serovar Hardjo. To reduce shedding of Leptospira interrogans serovar Hardjo in urine. To improve herd fertility when infertility is diagnosed as caused by Leptospira Hardjo.

Circulating antibody is detectable 14 days following the first injection and persists for 12 months following completion of the primary course.

Conjunctival challenge demonstrates 12 months cross protection against Leptospira borgpetersenii serovar hardjo (hardjo Bovis).

In addition to circulating antibody response, vaccination with Leptavoid-H also stimulates cell-mediated immunity to Leptospira borgpetersenii serovar hardjo which is maintained for at least five months and responds in the event of a challenge five months post vaccination.

Dosage & Administration

Dose:

• Cattle 2 ml. Minimum age of administration: 1 month.

Administration:

• By subcutaneous injection.
• The container should be well shaken to resuspend the precipitate before doses are withdrawn.
• The vaccine should be deposited beneath the skin covering the chest wall, well behind the shoulder, or beneath the skin covering the side of the neck.

Dosage schedule:

• The primary course consists of two doses with an interval of at least 4 weeks and not more than 6 weeks between them.
• Ideally the course should be completed in the spring before the main season of transmission of Leptospira hardjo.

Booster vaccination:

• Re-vaccination with a single dose should be given annually to maintain protection against infection and progressively reduce exposure in the herd.
• If the primary course is given later than the spring, the first booster should be given in the following spring and annually thereafter.

Youngstock vaccination:

• If the calves are inoculated before 5 months of age, a further primary course should be given at that age (allowing an interval of 4 weeks between vaccinations), as otherwise maternally derived antibodies may interfere with the immune response.
• Older calves not immediately exposed to infection can be given the initial course at any time, but it is advisable to complete vaccination shortly before the main season of transmission of leptospirosis.

To improve herd fertility:

• For maximum benefit the primary course should be completed within 12 months of infertility being diagnosed as caused by Leptospira hardjo.